Ama Fertility Center
Fertility Studies

The following are a variety of articles and abstracts published by the medical community that provide supporting evidence of the effectiveness of oriental medicine in treating a variety of health issues.






Pharmacological induction of ovulation is the traditional treatment for women with PCOS who want to become pregnant, but suffer from anovulation.


The aim of the present study was to elucidate the effect of EA on endocrinological and neuroendocrinological parameters as well as on anovulation in women with PCOS.


Twenty-six women, aged between 24 - 40 years, with PCOS and amenorrhea or oligomenorrhea and no more than four spontaneous bleedings per year and a typical ovarian ultrasonographic appearance of PCO, were included in this non-randomized, longitudinal, prospective study. Recording of vaginal bleedings and daily registrations of the basal body temperature (BBT) confirmed the outcome in terms of ovulation pattern throughout the entire study period. Blood samples for analyses of neuropeptides, gonadotropins, gonadal steroids were drawn from an antecubital vein. Ultrasound, body-mass index (BMI) and waist to hip ratio (WHR) measurements were made before the EA treatments and at the end of the study period.


Of 24 women, 9 experienced a good effect (38%) and displayed a mean of 0.66 ovulations per woman per month in the time during and after the EA period compared to a mean of 0.15 ovulations per woman per month before the EA period. The difference was significant. Fifteen women experienced no effect (62%), and the number of ovulations did not change in this group. Seven out of the 9 women that experienced good effect were clomiphene resistant. This suggests that EA might serve as a reasonable complement to first line therapies in ovulation induction.


Before EA, the group of women who would have a good effect were almost consistently characterized by a significantly lower BMI, and WHR, lower testosterone concentrations, testosterone/SHBG ratios and basal insulin concentrations and significantly higher serum concentrations of SHBG compared with those who would have no effect. So it was possible to identify a distinct subgroup of women who responded well to EA, i.e. those with a less distinct androgenic profile and a less pronounced metabolic disturbance. A significant decrease in LH/FSH ratio, testosterone and b-endorphin concentrations and a significant increase in prolactin concentrations were seen in all women, when concentrations before treatment were compared with concentrations 3 months after the EA period.


The present study shows that repeated EA treatments exert long-lasting effects on both endocrinological and neuroendocrinological parameters as well as on anovulation in women with PCOS.


Stener-Victorin E, Waldenstrom U, Tagnfors U, Lundeberg T, Lindstedt G, Janson PO. Effects of electro-acupuncture on anovulation in women with polycystic ovary syndrome. Acta Obstet Gynecol Scand 2000;79(3):180-8.